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What Does Zinc Have to Do With BPH, Cancer and Other Prostate Disease?
Did you know that over 60% of American men are zinc deficient? Men’s sperm contains 100 times more zinc than blood! Here’s another fact: You may have read somewhere that DHT (dihydrotestosterone) causes prostate enlargement.
LOOK! Maybe I’m getting ahead of myself, let’s start over.
- The prostate gland is unusual because it increases in size at various stages during most of a man’s life.
- The first stage of development is completed before or at birth, when the average prostate weighs about 1.5 grams.
- The second development occurs early during puberty, when the weight of the prostate gland reaches 11 grams.
- The third growth stage occurs during the mid-20s, when the weight of the prostate gland reaches approximately 18 grams.
- wth stage that begins when a man is in his 50s. The size varies depending on the man’s health.
- When a man is in his 70s, the prostate gland has reached its maximum weight of 31 grams.
There is another obvious gro
Although the prostate gland grows during most of a man’s life, urinary flow problems Benign Prostatic Hypertrophy (BPH) and/or cancer often appear only later in life. age 50 as the result of the last stage of development.
Medical researchers still do not know why the prostate gland enlarges during various growth spurts. However, there are two theories that try to explain this phenomenon. Both beliefs believe that hormonal changes over time are responsible.
(1) Changes in the normal balance of sex hormones. With age, the amount of the male hormone testosterone The main male hormone. Produced in the testicles, it is responsible for the growth and maturation of the first male reproductive system and the development of characteristics such as the low voice, the male genitalia of the body hair, a relative lack of fat under the skin, and larger bones. , decreases relative to the amount of circulating estrogen
A female hormone that is always present in small amounts in a man’s bloodstream.
There is some evidence to show that this relative increase in estrogen can strengthen the effects of the testosterone derivative DHT, which stimulates cell growth in the prostate gland and is produced when testosterone is made by a specific enzyme. As a result of estrogen and DHT together, cell growth and glandular swelling are increased.
WARNING: Ah-ha, DHT seems to be out of control and may be causing BPH. All wondering exactly what DHT is? Well here you go. DHT is a biological metabolite of the hormone testosterone, produced mainly in the prostate, glands, hair follicles, and adrenal glands by the enzyme 5a-reductase by reducing 4,5 double bond. DHT belongs to a class of chemicals called androgens, also known as androgenic hormones or testoids. Androgens are part of the biology of sex by stimulating and controlling the growth and maintenance of male characteristics. DHT is 3 times more powerful than testosterone; Testosterone is 5-10 times more abundant than adrenal androgens.
(2) Now here are 2 theories about DHT. The growth of the prostate gland requires the conversion of testosterone into DHT. In the presence of a special enzyme called 5-alpha reductase. As aging occurs, the amount of DHT in the prostate gland remains high, despite the circulating testosterone levels falling.
Some evidence supports the idea that high levels of prostate DHT can by itself stimulate cell growth and increase enlargement.
Now after the introduction we come to zinc. The role of zinc in many cellular processes, including cell division (ah – that means getting bigger – right?) and growth, immunity, and protection free radicals, have been well established. Zinc is the most abundant trace element in cells, and increasing evidence points to zinc’s important role in stability and function.
Zinc deficiency can weaken the body and affect growth, intelligence, and hormonal function. More than 2 billion people worldwide may be zinc deficient, you don’t have to be one of them.
Research has established a link between zinc deficiency and cancer is currently being established in humans, animals, and cell cultures. We also know that zinc status is affected in cancer patients compared to healthy people.
Zinc also seems to play an important role in maintaining the health of the prostate. Prostate cancer is the second leading cause of cancer in American men, and older men often have some abnormal prostate cancer. BPH may or may not be a precursor to prostate cancer. The normal human prostate cumulates the highest level of zinc of any tissue in the body, but we don’t know why. However, prostate cancer cells contain less zinc than normal prostates, and several studies have implicated zinc deficiency in the development and progression of prostate malignancy. There is also some evidence that a zinc-deficient diet is associated with a reduced risk of prostate cancer.
Zinc supplementation strategies will not only help prevent cancer, but may also play an important role in limiting its malignancy. As an antioxidant and part of many DNA repair proteins, zinc plays an important role in protecting DNA from damage. The current tolerable high intake of zinc is 40 mg/day, established by the US Institute of Medicine. Therefore, it is possible that studies in epidemiological studies can be in the toxicity of zinc intake. As with most treatments, higher doses don’t always equate to better results
As with the last sheet, zinc has some positive side effects such as: can be used to reduce cold symptoms, reduce the pain of colds, increase energy, treat ADHD in children, fight the hair loss and control conditions such as hypoglycemia and diabetes. The negative effects of zine can include: lowering your copper, iron and magnesium levels, lowering your immune system, and lowering your HDL (good cholesterol) levels. Less common side effects may include: abdominal pain, high blood pressure and nausea, fever, sore throat, mouth sores, weakness and fatigue.
There is some hope in clinical trials. Irving Bush, MD, professor of urology at the University of Health Sciences/Chicago Medical School, senior consultant at the School of Genitourinary Diseases in West Dundee, Illinois, and former president Respected by the Food and Drug Administration panels on gastroenterology, urology and dialysis, there has been a small study of the use of zinc in the treatment of BPH. The men in the study took 150 milligrams of inc sulfate daily for two months, followed by 50 to 100 milligrams per day as maintenance. Dr. Bush found that 14 of the 19 men had experienced prostate cancer.
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